Laboratory Services
Hepatitis B Envelope Antigen and Antibody
Print this pageUpdated Test Information:
| Test Description |
Hepatitis B Envelope Antigen and Antibody
|
|
|---|---|---|
| Synonym(s) |
UOW1183 |
|
| Test ID |
HBE
|
|
| General Information |
The Qualitative detection of Hepatitis B virus “e” antigen (HBeAg) and Hepatitis B virus “e” antibody (HBeAb) in human sera by the FDA approved LIASON® IgG Assay. The presence of HBeAg in serum is associated with presence of Dane particles and Hepatitis B virus (HBV) DNA polymerase enzyme. These markers suggest active HBV replication. Hepatitis B Surface antigen (HBsAg) positive and HBeAg positive persons are much more likely to transmit infections to others. The development of anti-HBe during acute Hepatitis B infection is a marker of resolution of illness. |
|
| Container Type |
5 mL Gold Top SST Also acceptable: 5 mL blood in ORANGE TOP rapid serum tube (RST), RED TOP tube or the following anticoagulants EDTA, heparin, or citrate. |
|
| Specimen Type |
Serum |
|
| Specimen Collection / Processing Instructions |
Harvest serum/plasma from whole blood within 24 hour or collection. Serum/plasma may be stored at 2-8°C (ice pack) for up to 3 days at room temperature (15-30°C) or up to 7 days. Freeze at -20°C or colder for long term storage. Do not freeze/thaw. |
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| Minimum Sample Volume |
0.6 mL serum or plasma |
|
| Unacceptable Specimen Conditions |
Cord blood, neonatal specimens, cadaver specimens, heat-inactivated specimens, or body fluids such as saliva, urine, amniotic fluid, or pleural fluid. Specimens with obvious microbial contamination, lipemic or are grossly hemolyzed. |
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| Department (code) |
Virology |
|
| Methodology |
The qualitative determination of HBeAg is a direct, sandwich chemiluminescence immunoassay (CLIA). The qualitative determination of anti-HBe is a competitive sandwich chemiluminescence immunoassay (CLIA) based on neutralization. |
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| Testing Schedule |
Once per week. |
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| Test Includes |
HEAG Hepatitis B e Ag |
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| CPT Code(s) |
86707, 87350 |
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| STAT Orderable (Y/N) |
No |
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| Performing Lab |
UW |
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| LOINC Code(s) |
